NGF/BDNF chimeric proteins: analysis of neurotrophin specificity by homolog-scanning mutagenesis

Despite their extensive sequence identities at the amino acid level (approximately 55%), NGF and brain-derived neurotrophic factor (BDNF) display distinct neuronal specificity toward neurons of both the PNS and CNS. To explore which region(s) within these neurotrophic factors might determine their d...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Suter, U, Angst, C, Tien, CL, Drinkwater, CC, Lindsay, RM, Shooter, EM
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1992
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575690/
https://ncbi.nlm.nih.gov/pubmed/1729439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-01-00306.1992
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