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Human rod photoreceptor cGMP-gated channel: amino acid sequence, gene structure, and functional expression

Phototransduction in retinal rods involves a G-protein-mediated signaling cascade that leads to cGMP hydrolysis and the closure of a cGMP-gated channel. This channel has recently been purified from bovine retina and molecularly cloned (Kaupp et al., 1989). We report here the cloning of cDNA and geno...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Dhallan, RS, Macke, JP, Eddy, RL, Shows, TB, Reed, RR, Yau, KW, Nathans, J
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575660/
https://ncbi.nlm.nih.gov/pubmed/1379636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-08-03248.1992
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