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Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins

The current model of polarized plasma membrane protein sorting in epithelial cells has been largely generated on the basis of experiments characterizing the polarized distribution of a relatively small number of overexpressed model proteins under various experimental conditions. Thus, the possibilit...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Caceres, Paulo S., Gravotta, Diego, Zager, Patrick J., Dephoure, Noah, Rodriguez-Boulan, Enrique
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575629/
https://ncbi.nlm.nih.gov/pubmed/31142645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821076116
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