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Perfluorocarbon nanoparticle-mediated platelet inhibition promotes intratumoral infiltration of T cells and boosts immunotherapy

Cancer immunotherapy can stimulate and enhance the ability of the immune system to recognize, arrest, and eliminate tumor cells. Immune checkpoint therapies (e.g., PD-1/PD-L1) have shown an unprecedented and durable clinical response rate in patients among various cancer types. However, a large frac...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Zhou, Zaigang, Zhang, Baoli, Zai, Wenjing, Kang, Lin, Yuan, Ahu, Hu, Yiqiao, Wu, Jinhui
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575596/
https://ncbi.nlm.nih.gov/pubmed/31142648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901987116
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