Caspase-8 promotes c-Rel–dependent inflammatory cytokine expression and resistance against Toxoplasma gondii

Caspase-8 is a key integrator of cell survival and cell death decisions during infection and inflammation. Following engagement of tumor necrosis factor superfamily receptors or certain Toll-like receptors (TLRs), caspase-8 initiates cell-extrinsic apoptosis while inhibiting RIPK3-dependent programm...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: DeLaney, Alexandra A., Berry, Corbett T., Christian, David A., Hart, Andrew, Bjanes, Elisabet, Wynosky-Dolfi, Meghan A., Li, Xinyuan, Tummers, Bart, Udalova, Irina A., Chen, Youhai H., Hershberg, Uri, Freedman, Bruce D., Hunter, Christopher A., Brodsky, Igor E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575527/
https://ncbi.nlm.nih.gov/pubmed/31147458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820529116
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