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Effects of sphingosine, staurosporine, and phorbol ester on neurites of rat sympathetic neurons growing in compartmented cultures

Local application of sphingosine (1–10 microM), an inhibitor of protein kinase C, to NGF-supplied, distal neurites of rat sympathetic neurons in compartmented cultures caused their retraction and/or degeneration within 24 hr. This effect was specific for distal neurites because sphingosine (even at...

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Foilsithe in:J Neurosci
Main Authors: Campenot, RB, Walji, AH, Draker, DD
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 1991
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575378/
https://ncbi.nlm.nih.gov/pubmed/2010808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-04-01126.1991
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