Implantable multireservoir device with stimulus-responsive membrane for on-demand and pulsatile delivery of growth hormone

Implantable devices for on-demand and pulsatile drug delivery have attracted considerable attention; however, many devices in clinical use are embedded with the electronic units and battery inside, hence making them large and heavy for implantation. Therefore, we propose an implantable device with m...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lee, Seung Ho, Piao, Huiyan, Cho, Yong Chan, Kim, Se-Na, Choi, Goeun, Kim, Cho Rim, Ji, Han Bi, Park, Chun Gwon, Lee, Cheol, Shin, Chong In, Koh, Won-Gun, Choy, Young Bin, Choy, Jin-Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575234/
https://ncbi.nlm.nih.gov/pubmed/31123147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906931116
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