5-Methyltetrahydrofolate in Maternal Diets Alters DNA Methylation Potential and Increases Later Life Weight Gain and Food Intake in Wistar Rat Dams and Female Offspring (P11-022-19)

OBJECTIVES: Diet during pregnancy programs the mother and offspring post-weaning (PW). Folic acid (FA, synthetic folate) mediates DNA methylation (DNAm) reactions and high intakes, simulating those consumed by American women, lead to epigenetic dysregulation of energy metabolic pathways. 5-methyltet...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Pannia, Emanuela, Hammoud, Rola, Kubant, Ruslan, Sa, Jong, Yang, Neil, Ho, Mandy, Chatterjee, Diptendu, Pausova, Zdenka, Arning, Erland, Bottiglieri, Teodoro, Anderson, G Harvey
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Maternal, Perinatal and Pediatric Nutrition
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6574692/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzz048.P11-022-19
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