Microbial mRNAs in Bovine Milk Exosomes Are Bioavailable in Humans and Mice and Increase Survival of Mice Challenged with Influenza A (OR12-07-19)

OBJECTIVES: Exosomes are natural nanoparticles that facilitate cell-to-cell communication by transferring RNAs from donor to recipient cells. Previous studies focused on microRNA cargos and disregarded mRNAs. Exosomes and RNA cargos may be absorbed from milk. RNAs elicit antiviral responses by activ...

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Veröffentlicht in:Curr Dev Nutr
Hauptverfasser: Wu, Di, Zhou, Fang, Upadhyaya, Bijaya, Shu, Jiang, Mutai, Ezra, Cui, Juan, Zempleni, Janos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Nutritional Immunology and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6574010/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzz049.OR12-07-19
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