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Neurotrophins Protect Cultured Cerebellar Granule Neurons against the Early Phase of Cell Death by a TwoComponent Mechanism

Cerebellar granule neurons cultured with serum develop a mature neuronal phenotype, including stimulus-coupled release of glutamate, and depend on elevated potassium for survival. We find that cells cultured with serum undergo two phases of cell death. By 6 din vitro, 30–50% of the cells present are...

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Publicado en:J Neurosci
Autores principales: Courtney, Michael J., Åkerman, Karl E. O., Coffey, Eleanor T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573533/
https://ncbi.nlm.nih.gov/pubmed/9151737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-11-04201.1997
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