Diminished Inflammation and Nociceptive Pain with Preservation of Neuropathic Pain in Mice with a Targeted Mutation of the Type I Regulatory Subunit of cAMP-Dependent Protein Kinase

To assess the contribution of PKA to injury-induced inflammation and pain, we evaluated nociceptive responses in mice that carry a null mutation in the gene that encodes the neuronal-specific isoform of the type I regulatory subunit (RIβ) of PKA. Acute pain indices did not differ in the RIβ PKA muta...

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Publicado en:J Neurosci
Autores principales: Malmberg, Annika B., Brandon, Eugene P., Idzerda, Rejean L., Liu, Hantao, McKnight, G. Stanley, Basbaum, Allan I.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1997
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573437/
https://ncbi.nlm.nih.gov/pubmed/9295392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-19-07462.1997
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