BDNF and NT-4/5 Prevent Atrophy of Rat Rubrospinal Neurons after Cervical Axotomy, Stimulate GAP-43 and Tα1-Tubulin mRNA Expression, and Promote Axonal Regeneration

Rubrospinal neurons (RSNs) undergo a marked atrophy in the second week after cervical axotomy. This delayed atrophy is accompanied by a decline in the expression of regeneration-associated genes such as GAP-43 and Tα1-tubulin, which are initially elevated after injury. These responses may reflect a...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kobayashi, Nao R., Fan, Da-Peng, Giehl, Klaus M., Bedard, Annie M., Wiegand, Stanley J., Tetzlaff, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573396/
https://ncbi.nlm.nih.gov/pubmed/9391013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-24-09583.1997
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