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Heterozygous Peripheral Myelin Protein 22-Deficient Mice Are Affected by a Progressive Demyelinating Tomaculous Neuropathy

Hereditary neuropathy with liability to pressure palsy (HNPP) is associated with a heterozygous 1.5 megabase deletion on chromosome 17 that includes the peripheral myelin protein (PMP) genePMP22. We show that heterozygous PMP22 knock-out mice, which carry only one functional pmp22 allele and thus ge...

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Pubblicato in:J Neurosci
Autori principali: Adlkofer, Katrin, Frei, Regula, Neuberg, Dirk H.-H., Zielasek, Jürgen, Toyka, Klaus V., Suter, Ueli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573352/
https://ncbi.nlm.nih.gov/pubmed/9169527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-12-04662.1997
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