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Differential Susceptibility to Neurotoxicity Mediated by Neurotrophins and Neuronal Nitric Oxide Synthase

NMDA neurotoxicity, which is mediated, in part, by formation of nitric oxide (NO) via activation of neuronal NO synthase (nNOS), is modulated by neurotrophins. nNOS expression in rat and mouse primary neuronal cultures grown on a glial feeder layer is significantly less than that of neurons grown on...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Samdani, Amer F., Newcamp, Cheryl, Resink, Annelies, Facchinetti, Fabrizio, Hoffman, Brian E., Dawson, Valina L., Dawson, Ted M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573350/
https://ncbi.nlm.nih.gov/pubmed/9169524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-12-04633.1997
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