Activation of the CED3/ICE-Related Protease CPP32 in Cerebellar Granule Neurons Undergoing Apoptosis But Not Necrosis

Neuronal apoptosis occurs during nervous system development and after pathological insults to the adult nervous system. Inhibition of CED3/ICE-related proteases has been shown to inhibit neuronal apoptosisin vitro and in vivo, indicating a role for these cysteine proteases in neuronal apoptosis. We...

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Publicado en:J Neurosci
Autores principales: Armstrong, Robert C., Aja, Teresa J., Hoang, Kim D., Gaur, Smita, Bai, Xu, Alnemri, Emad S., Litwack, Gerald, Karanewsky, Donald S., Fritz, Lawrence C., Tomaselli, Kevin J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573236/
https://ncbi.nlm.nih.gov/pubmed/8987778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-02-00553.1997
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