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A Novel Allosteric Potentiator of AMPA Receptors: 4-[2-(Phenylsulfonylamino)ethylthio]-2,6-Difluoro-Phenoxyacetamide

We report that a novel sulfonylamino compound, 4-[2-(phenylsulfonylamino)ethylthio]-2,6-difluoro-phenoxyacetamide (PEPA), selectively potentiates glutamate receptors of the AMPA subtype. PEPA (1–200 μm) dose dependently potentiated glutamate-evoked currents in Xenopus oocytes expressing AMPA (GluRA–...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sekiguchi, Masayuki, Fleck, Mark W., Mayer, Mark L., Takeo, Jiro, Chiba, Yoshiyuki, Yamashita, Shinya, Wada, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573208/
https://ncbi.nlm.nih.gov/pubmed/9221774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-15-05760.1997
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