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Noxious Cutaneous Thermal Stimuli Induce a Graded Release of Endogenous Substance P in the Spinal Cord: Imaging Peptide ActionIn Vivo

Dorsal root ganglia (DRG) neurons synthesize and transport substance P (SP) to the spinal cord where it is released in response to intense noxious somatosensory stimuli. We have shown previously that SP release in vivo causes a rapid and reversible internalization of SP receptors (SPRs) in dorsal ho...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Allen, Brian J., Rogers, Scott D., Ghilardi, Joseph R., Menning, Patrick M., Kuskowski, Michael A., Basbaum, Allan I., Simone, Donald A., Mantyh, Patrick W.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573203/
https://ncbi.nlm.nih.gov/pubmed/9221788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-15-05921.1997
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