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Ionized Intracellular Calcium Concentration Predicts Excitotoxic Neuronal Death: Observations with Low-Affinity Fluorescent Calcium Indicators

Cytosolic calcium ([Ca(2+)](i)) is an important mediator of neuronal signal transduction, participating in diverse biochemical reactions that elicit changes in synaptic efficacy, metabolic rate, and gene transcription. Excessive [Ca(2+)](i) also has been implicated as a cause of acute neuronal injur...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hyrc, Krzysztof, Handran, Shawn D., Rothman, Steven M., Goldberg, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573145/
https://ncbi.nlm.nih.gov/pubmed/9254679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-17-06669.1997
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