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CuH-Catalyzed Enantioselective Ketone Allylation with 1,3-Dienes: Scope, Mechanism, and Applications

Chiral tertiary alcohols are important building blocks for the synthesis of pharmaceutical agents and biologically active natural products. The addition of carbon nucleophiles to ketones is the most common approach to tertiary alcohol synthesis, but traditionally relies on stoichiometric organometal...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Li, Chengxi, Liu, Richard Y., Jesikiewicz, Luke T., Yang, Yang, Liu, Peng, Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572726/
https://ncbi.nlm.nih.gov/pubmed/30817137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b01784
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