Synthesis and Cytotoxic Evaluation of 3-Methylidenechroman-4-ones

In the search for new anticancer agents, a library of variously substituted 3-methylidenechroman-4-ones was synthesized using Horner–Wadsworth–Emmons methodology. Acylation of diethyl methylphosphonate with selected ethyl salicylates furnished 3-diethoxyphosphorylchromen-4-ones which were next used...

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Vydáno v:Molecules
Hlavní autoři: Kędzia, Jacek, Bartosik, Tomasz, Drogosz, Joanna, Janecka, Anna, Krajewska, Urszula, Janecki, Tomasz
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572547/
https://ncbi.nlm.nih.gov/pubmed/31096601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24101868
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