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Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX(3)CL1/CX(3)CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion

Background: Metabolic syndrome is associated with low-grade systemic inflammation, which is a key driver of premature atherosclerosis. We characterized immune cell behavior in metabolic syndrome, its consequences, and the potential involvement of the CX(3)CL1/CX(3)CR1 and CCL2/CCR2 chemokine axes. M...

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Publicat a:J Clin Med
Autors principals: Marques, Patrice, Collado, Aida, Martinez-Hervás, Sergio, Domingo, Elena, Benito, Esther, Piqueras, Laura, Real, José T., Ascaso, Juan F., Sanz, Maria-Jesus
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572270/
https://ncbi.nlm.nih.gov/pubmed/31109070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8050708
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