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Structures of soluble rabbit neprilysin complexed with phosphoramidon or thiorphan

Neutral endopeptidase (neprilysin; NEP) is a proteinase that cleaves a wide variety of peptides and has been implicated in Alzheimer’s disease, cardiovascular conditions, arthritis and other inflammatory diseases. The structure of the soluble extracellular domain (residues 55–750) of rabbit neprilys...

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Detalles Bibliográficos
Publicado en:Acta Crystallogr F Struct Biol Commun
Autores principales: Labiuk, Shaunivan L., Sygusch, Jurgen, Grochulski, Pawel
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572095/
https://ncbi.nlm.nih.gov/pubmed/31204686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X19006046
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