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Discovery of Cisplatin Binding to Thymine and Cytosine on a Single-Stranded Oligodeoxynucleotide by High Resolution FT-ICR Mass Spectrometry
The clinically widely-used anticancer drug, cisplatin, binds strongly to DNA as a DNA-damaging agent. Herein, we investigated the interaction of cisplatin with a 15-mer single-stranded C,T-rich oligodeoxynucleotide, 5′-CCTT(4)CTT(7)G(8)C(9)T(10)TCTCC-3′ (ODN15), using ultra-high resolution Fourier t...
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| Udgivet i: | Molecules |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6571787/ https://ncbi.nlm.nih.gov/pubmed/31091778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24101852 |
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