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Pharmacodynamics of Five Anthraquinones (Aloe-emodin, Emodin, Rhein, Chysophanol, and Physcion) and Reciprocal Pharmacokinetic Interaction in Rats with Cerebral Ischemia

(1) Background: Rhubarb anthraquinones—a class of components with neuroprotective function—can be used to alleviate cerebral ischemia reperfusion injury. (2) Methods: The three pharmacodynamic indicators are neurological function score, brain water content, and cerebral infarction area; UPLC-MS/MS w...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Li, Rong-Rong, Liu, Xue-Fang, Feng, Su-Xiang, Shu, Sheng-Nan, Wang, Pei-Yang, Zhang, Na, Li, Jian-Sheng, Qu, Ling-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571683/
https://ncbi.nlm.nih.gov/pubmed/31108858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24101898
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