Mineralocorticoid Receptor May Regulate Glucose Homeostasis through the Induction of Interleukin-6 and Glucagon-Like peptide-1 in Pancreatic Islets

Because the renin-angiotensin-aldosterone system influences glucose homeostasis, the mineralocorticoid receptor (MR) signal in pancreatic islets may regulate insulin response upon glucose load. Glucagon-like peptide-1 (GLP-1) production is stimulated by interleukin-6 (IL-6) in pancreatic α-cells. To...

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Publicat a:J Clin Med
Autors principals: Goto, Rieko, Kondo, Tatsuya, Ono, Kaoru, Kitano, Sayaka, Miyakawa, Nobukazu, Watanabe, Takuro, Sakaguchi, Masaji, Sato, Miki, Igata, Motoyuki, Kawashima, Junji, Motoshima, Hiroyuki, Matsumura, Takeshi, Shimoda, Seiya, Araki, Eiichi
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571682/
https://ncbi.nlm.nih.gov/pubmed/31091693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8050674
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