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tRNA Fragments Show Intertwining with mRNAs of Specific Repeat Content and Have Links to Disparities

tRNA-derived fragments (tRFs) are a class of potent regulatory RNAs. We mined the datasets from The Cancer Genome Atlas representing 32 cancer types with a deterministic and exhaustive pipeline for tRNA fragments. We found that mitochondrial tRNAs contribute disproportionally more tRFs than the nucl...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Telonis, Aristeidis G., Loher, Phillipe, Magee, Rogan, Pliatsika, Venetia, Londin, Eric, Kirino, Yohei, Rigoutsos, Isidore
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571059/
https://ncbi.nlm.nih.gov/pubmed/30996049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0789
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