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Metformin prevents vascular damage in hypertension through the AMPK/ER stress pathway

Metformin is an antidiabetic drug. However, the pleiotropic beneficial effects of metformin in nondiabetic models still need to be defined. The objective of this study is to investigate the effect of metformin on angiotensin II (Ang II)-induced hypertension and cardiovascular diseases. Mice were inf...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hypertens Res
Hauptverfasser: Chen, Cheng, Kassan, Adam, Castañeda, Diana, Gabani, Mohanad, Choi, Soo-Kyoung, Kassan, Modar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571038/
https://ncbi.nlm.nih.gov/pubmed/30664704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41440-019-0212-z
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