Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes

BACKGROUND: Adult hippocampal neurogenesis plays an important role in synaptic plasticity and cogntive function. We reported that higher numbers of neural stem cells (NSC) in the hippocampus of cognitively-intact individuals with high Alzheimer’s disease (AD) pathology (plaques and tangles) is assoc...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Neurodegener
Auteurs principaux: Micci, Maria-Adelaide, Krishnan, Balaji, Bishop, Elizabeth, Zhang, Wen-Ru, Guptarak, Jutatip, Grant, Auston, Zolochevska, Olga, Tumurbaatar, Batbayar, Franklin, Whitney, Marino, Claudia, Widen, Steven G., Luthra, Arjun, Kernie, Steven G., Taglialatela, Giulio
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570890/
https://ncbi.nlm.nih.gov/pubmed/31200742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0322-8
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