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Differential involvement of protein kinase C isozymes in Alzheimer's disease

Decreased levels of protein kinase C (PKC) and a reduction in the in vitro phosphorylation of a Mr 86,000 protein (P86), the major PKC substrate, are biochemical characteristics of brain tissue from patients with Alzheimer's disease (AD) (Cole et al., 1988). In the current study, we utilized an...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Masliah, E, Cole, G, Shimohama, S, Hansen, L, DeTeresa, R, Terry, RD, Saitoh, T
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570390/
https://ncbi.nlm.nih.gov/pubmed/2376771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-07-02113.1990
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