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Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors

Excitatory amino acid (EAA)-mediated synaptic transmission is the most prevalent excitatory system within the mammalian brain. Activation of EAA receptors has been postulated to contribute to neuronal cell death in stroke, epilepsy, hypoglycemia, and Huntington's disease. Kynurenic acid is an e...

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Pubblicato in:J Neurosci
Autori principali: Swartz, KJ, During, MJ, Freese, A, Beal, MF
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570241/
https://ncbi.nlm.nih.gov/pubmed/2168940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-09-02965.1990
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