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Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors

Excitatory amino acid (EAA)-mediated synaptic transmission is the most prevalent excitatory system within the mammalian brain. Activation of EAA receptors has been postulated to contribute to neuronal cell death in stroke, epilepsy, hypoglycemia, and Huntington's disease. Kynurenic acid is an e...

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Опубликовано в: :J Neurosci
Главные авторы: Swartz, KJ, During, MJ, Freese, A, Beal, MF
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 1990
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570241/
https://ncbi.nlm.nih.gov/pubmed/2168940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-09-02965.1990
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