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Interaction of forskolin with voltage-gated K+ channels in PC12 cells

Forskolin (FSK) directly blocks a distinct class of voltage-dependent K+ channels in pheochromocytoma cells. We have studied the biophysical mechanism of FSK action on these channels. The mean open duration decreased linearly with [FSK], indicating that a single molecule of FSK interacts with a sing...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Garber, SS, Hoshi, T, Aldrich, RW
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570191/
https://ncbi.nlm.nih.gov/pubmed/2213145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-10-03361.1990
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