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Chronic naltrexone treatment increases expression of preproenkephalin and preprotachykinin mRNA in discrete brain regions
Long-term blockade of brain opioid receptors by the opiate antagonist naltrexone increases methionine-enkephalin content in the striatum and nucleus accumbens (Tempel et al., 1984). To determine whether these changes in peptide levels reflect increased peptide synthesis, we examined preproenkephalin...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6570123/ https://ncbi.nlm.nih.gov/pubmed/2319301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-03-00741.1990 |
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