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Inhibition of agrin-induced acetylcholine-receptor aggregation by heparin, heparan sulfate, and other polyanions

Heparin and heparan sulfate have been shown to block nerve-induced acetylcholine-receptor (AChR) aggregation at developing neuromuscular junctions. We found that heparin, heparan sulfate, and a wide variety of other polyanions also inhibited agrin-induced AChR aggregation. The more highly charged th...

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Pubblicato in:J Neurosci
Autore principale: Wallace, BG
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570091/
https://ncbi.nlm.nih.gov/pubmed/1700081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-11-03576.1990
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