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Brain IL-1-induced immunosuppression occurs through activation of both pituitary-adrenal axis and sympathetic nervous system by corticotropin- releasing factor

Intracerebroventricular infusion of femtomolar quantities of interleukin-1 (IL-1) or stimulated release of endogenous IL-1 in the brain suppresses various cellular immune responses, decreasing natural killer cell (NK) activity, response to mitogen, and interleukin-2 production of splenic and blood l...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Sundar, SK, Cierpial, MA, Kilts, C, Ritchie, JC, Weiss, JM
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1990
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570088/
https://ncbi.nlm.nih.gov/pubmed/2230954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-11-03701.1990
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