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Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R- (-)2,5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin

The radioligand binding characteristics of 125I-R-(-)4-iodo-2,5- dimethoxyphenylisopropylamine [125I-R-(-)DOI] and 3H-ketanserin were compared in rat and bovine cortical membranes. In rat cortex, 125I-R-(- )DOI labels a relatively low density of binding sites (Bmax = 2.5 +/- 0.2 pmol/gm tissue) with...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: McKenna, DJ, Peroutka, SJ
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6569888/
https://ncbi.nlm.nih.gov/pubmed/2795135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.09-10-03482.1989
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