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Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D- aspartate receptor antagonist AP5

This paper reports a series of 5 experiments concerned with a possible role for N-methyl-D-aspartate (NMDA) receptors in certain types of learning. The results show that chronic intraventricular infusion of the NMDA receptor antagonist D,L-2-amino-5-phosphonopentanoic acid (D,L- AP5) caused an impai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
1. Verfasser: Morris, RG
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1989
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6569656/
https://ncbi.nlm.nih.gov/pubmed/2552039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.09-09-03040.1989
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