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K-252a: a specific inhibitor of the action of nerve growth factor on PC 12 cells

K-252a, a kinase inhibitor isolated from the culture broth of Nocardiopsis sp., selectively inhibits the actions of nerve growth factor (NGF) on PC 12 cells. At a concentration of 200 nM, K-252a prevents neurite generation initiated by NGF, but not neurite generation produced by fibroblast growth fa...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Koizumi, S, Contreras, ML, Matsuda, Y, Hama, T, Lazarovici, P, Guroff, G
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6569309/
https://ncbi.nlm.nih.gov/pubmed/3339434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.08-02-00715.1988
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