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Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil

The neuroprotective effects of MK-801, a noncompetitive antagonist of N- methyl-D-aspartate (NMDA) receptors, were evaluated in models of cerebral ischemia using Mongolian gerbils. Bilateral occlusion of the carotid arteries for a period of 5 min resulted in a consistent pattern of degeneration of h...

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Publicat a:J Neurosci
Autors principals: Gill, R, Foster, AC, Woodruff, GN
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6569187/
https://ncbi.nlm.nih.gov/pubmed/3312511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.07-10-03343.1987
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