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Characterization of a novel 3H-5-hydroxytryptamine binding site subtype in bovine brain membranes

3H-5-Hydroxytryptamine (5-HT) binding sites were analyzed in bovine brain membranes. The addition of either the 5-HT1A-selective drug 8-OH- DPAT (100 nM) or the 5-HT1C-selective drug mesulergine (100 nM) to the assay resulted in a 5–10% decrease in specific 3H-5-HT binding. Scatchard analysis reveal...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Heuring, RE, Peroutka, SJ
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6569069/
https://ncbi.nlm.nih.gov/pubmed/2951504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.07-03-00894.1987
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