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Nerve growth factor increases the number of functional Na channels and induces TTX-resistant Na channels in PC12 pheochromocytoma cells

The PC12 clone is a line of rat pheochromocytoma cells that undergoes neuronal differentiation in the presence of NGF protein. In the absence of NGF, PC12 cells are electrically inexcitable, while after several weeks of NGF treatment they develope Na+ action potentials. Past estimates made by measur...

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Pubblicato in:J Neurosci
Autori principali: Rudy, B, Kirschenbaum, B, Rukenstein, A, Greene, LA
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1987
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568881/
https://ncbi.nlm.nih.gov/pubmed/2439661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.07-06-01613.1987
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