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Expression of the jimpy gene in the spinal cords of heterozygous female mice. I. An early myelin deficit followed by compensation

The jimpy mutation results in severe hypomyelination throughout the CNS of hemizygous male mice. In the female carrier of the jimpy gene, partial hypomyelination is predicted as a consequence of genetic mosaicism resulting from random X-chromosome inactivation. The spinal cord of the female carrier...

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Библиографические подробности
Опубликовано в: :J Neurosci
Главные авторы: Bartlett, WP, Skoff, RP
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 1986
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568783/
https://ncbi.nlm.nih.gov/pubmed/3760935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.06-10-02802.1986
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