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Expression of the jimpy gene in the spinal cords of heterozygous female mice. I. An early myelin deficit followed by compensation

The jimpy mutation results in severe hypomyelination throughout the CNS of hemizygous male mice. In the female carrier of the jimpy gene, partial hypomyelination is predicted as a consequence of genetic mosaicism resulting from random X-chromosome inactivation. The spinal cord of the female carrier...

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Pubblicato in:J Neurosci
Autori principali: Bartlett, WP, Skoff, RP
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1986
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568783/
https://ncbi.nlm.nih.gov/pubmed/3760935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.06-10-02802.1986
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