Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer genome analysis

In addition to conventional cytology, liquid-based cytology (LBC) is also used for immunocytochemistry and gene analysis. However, an appropriate method to obtain high quality DNA for next-generation sequencing (NGS) using LBC specimens remains controversial. We determined the optimal conditions for...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Akahane, Toshiaki, Yamaguchi, Tomomi, Kato, Yasutaka, Yokoyama, Seiya, Hamada, Taiji, Nishida, Yukari, Higashi, Michiyo, Nishihara, Hiroshi, Suzuki, Shinsuke, Ueno, Shinichi, Tanimoto, Akihide
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568385/
https://ncbi.nlm.nih.gov/pubmed/31199826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217724
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