Laser Capture Microdissection and RNA-Seq Analysis: High Sensitivity Approaches to Explain Histopathological Heterogeneity in Human Glioblastoma FFPE Archived Tissues

Laser capture microdissection (LCM) coupled with RNA-seq is a powerful tool to identify genes that are differentially expressed in specific histological tumor subtypes. To better understand the role of single tumor cell populations in the complex heterogeneity of glioblastoma, we paired microdissect...

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Veröffentlicht in:Front Oncol
Hauptverfasser: Civita, Prospero, Franceschi, Sara, Aretini, Paolo, Ortenzi, Valerio, Menicagli, Michele, Lessi, Francesca, Pasqualetti, Francesco, Naccarato, Antonio Giuseppe, Mazzanti, Chiara Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568189/
https://ncbi.nlm.nih.gov/pubmed/31231613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00482
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