An oxygen self-sufficient NIR-responsive nanosystem for enhanced PDT and chemotherapy against hypoxic tumors

The efficacy of photodynamic therapy and chemotherapy is largely limited by oxygen deficiency in the hypoxic tumor microenvironment. To solve these problems, we fabricated a novel NIR-responsive nanosystem which could co-deliver oxygen and anticancer drug DOX. An oxygen self-sufficient amphiphile (F...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Yang, Guoliang, Tian, Jia, Chen, Chao, Jiang, Dawei, Xue, Yudong, Wang, Chaochao, Gao, Yun, Zhang, Weian
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2019
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568044/
https://ncbi.nlm.nih.gov/pubmed/31293763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00985j
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