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Proteolysis mediated by the membrane‐integrated ATP‐dependent protease FtsH has a unique nonlinear dependence on ATP hydrolysis rates

ATPases associated with diverse cellular activities (AAA+) proteases utilize ATP hydrolysis to actively unfold native or misfolded proteins and translocate them into a protease chamber for degradation. This basic mechanism yields diverse cellular consequences, including the removal of misfolded prot...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Yang, Yiqing, Gunasekara, Mihiravi, Muhammednazaar, Shaima, Li, Zhen, Hong, Heedeok
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567685/
https://ncbi.nlm.nih.gov/pubmed/31008538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3629
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