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Prediction of activity and specificity of CRISPR-Cpf1 using convolutional deep learning neural networks
BACKGROUND: CRISPR-Cpf1 has recently been reported as another RNA-guided endonuclease of class 2 CRISPR-Cas system, which expands the molecular biology toolkit for genome editing. However, most of the online tools and applications to date have been developed primarily for the Cas9. There are a limit...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | BMC Bioinformatics |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6567654/ https://ncbi.nlm.nih.gov/pubmed/31195957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2939-6 |
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