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Hydrogen-rich saline ameliorated LPS-induced acute lung injury via autophagy inhibition through the ROS/AMPK/mTOR pathway in mice

Over-activation of autophagy due to increased levels of reactive oxygen species is a key mechanism of lipopolysaccharide-induced acute lung injury. Hydrogen-rich saline, an antioxidant, has been proved to be an effective agent for the prevention of acute lung injury, but the underlying mechanism rem...

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Détails bibliographiques
Publié dans:Exp Biol Med (Maywood)
Auteurs principaux: Wang, Yong, Zhang, Jinghua, Bo, Jinsong, Wang, Xuefen, Zhu, Jingnan
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567588/
https://ncbi.nlm.nih.gov/pubmed/31042074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219847941
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