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Elevated level of mitochondrial reactive oxygen species via fatty acid β-oxidation in cancer stem cells promotes cancer metastasis by inducing epithelial–mesenchymal transition

BACKGROUND: Cancer stem cells (CSCs) play a critical role in tumor development and progression and are involved in cancer metastasis. The role of reactive oxygen species (ROS) in CSCs and cancer metastasis remains controversial. The aim of the present study was to investigate the correlation between...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Wang, Caihua, Shao, Liming, Pan, Chi, Ye, Jun, Ding, Zonghui, Wu, Jia, Du, Qin, Ren, Yuezhong, Zhu, Chunpeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567550/
https://ncbi.nlm.nih.gov/pubmed/31196164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1265-2
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