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Bone Metastasis Phenotype and Growth Undergo Regulation by Micro-Environment Stimuli: Efficacy of Early Therapy with HGF or TGFβ1-Type I Receptor Blockade

Hepatocyte growth factor (HGF) and transforming growth factor β1 (TGFβ1) are biological stimuli of the micro-environment which affect bone metastasis phenotype through transcription factors, but their influence on the growth is scarcely known. In a xenograft model prepared with 1833 bone metastatic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Bendinelli, Paola, Maroni, Paola, Dall’Olio, Valentina, Matteucci, Emanuela, Desiderio, Maria Alfonsina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567054/
https://ncbi.nlm.nih.gov/pubmed/31121879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102520
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