Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death

High levels of heme oxygenase (HO)-1 have been frequently reported in different human cancers, playing a major role in drug resistance and regulation of cancer cell redox homeostasis. Metformin (MET), a drug widely used for type 2 diabetes, has recently gained interest for treating several cancers....

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Raffaele, Marco, Pittalà, Valeria, Zingales, Veronica, Barbagallo, Ignazio, Salerno, Loredana, Li Volti, Giovanni, Romeo, Giuseppe, Carota, Giuseppe, Sorrenti, Valeria, Vanella, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566853/
https://ncbi.nlm.nih.gov/pubmed/31137785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102593
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